Purpose:
The official study aimed to determine if oral zinc supplementation could alter the effectiveness and duration of botulinum toxin treatments.
Methods: The scientists conducted a randomized double-blind, placebo-controlled, crossover pilot study to evaluate the efficacy of three types of botulinum toxin (onabotulinumtoxinA, abobotulinumtoxinA, and rimabotulinumtoxinB) after participants received Zinc supplement, or a lactulose placebo. The study involved individuals undergoing treatment for wrinkles, eye muscle spasms, and facial muscle spasms.
Results: Out of seventy-seven patients, 92% of those who took Zinc had their botulinum toxin effects last about 30% longer on average. Also, 84% of them said they felt the effects were stronger. In contrast, patients who took the lactulose placebo didn’t see significant changes in how long the effects lasted or how well they worked. Some patients had such a big change from the Zinc that the study was stopped early.
Conclusions: This study suggests that taking Zinc supplements might help botulinum toxin treatments absorb better and last slightly longer for wrinkles, eye muscle spasms, and facial muscle spasms.
